Mapping autism risk loci using genetic linkage and chromosomal rearrangements.
Identifieur interne : 000759 ( France/Analysis ); précédent : 000758; suivant : 000760Mapping autism risk loci using genetic linkage and chromosomal rearrangements.
Auteurs : Peter Szatmari [Canada] ; Andrew Paterson [Canada] ; Lonnie Zwaigenbaum [Canada] ; Wendy Roberts [Canada] ; Jessica Brian [Canada] ; Xiao-Qing Liu [Canada] ; John Vincent [Canada] ; Jennifer Skaug [Canada] ; Ann Thompson [Canada] ; Lili Senman [Canada] ; Lars Feuk [Canada] ; Cheng Qian [Canada] ; Susan Bryson [Canada] ; Marshall Jones [États-Unis] ; Christian Marshall [Canada] ; Stephen Scherer [Canada] ; Veronica Vieland [États-Unis] ; Christopher Bartlett [États-Unis] ; La Vonne Mangin [États-Unis] ; Rhinda Goedken [États-Unis] ; Alberto Segre [États-Unis] ; Margaret Pericak-Vance [États-Unis] ; Michael Cuccaro [États-Unis] ; John Gilbert [États-Unis] ; Harry Wright [États-Unis] ; Ruth Abramson [États-Unis] ; Catalina Betancur [France] ; Thomas Bourgeron [France] ; Christopher Gillberg [Suède] ; Marion Leboyer [France] ; Joseph Buxbaum [États-Unis] ; Kenneth Davis [États-Unis] ; Eric Hollander [États-Unis] ; Jeremy Silverman [États-Unis] ; Joachim Hallmayer [États-Unis] ; Linda Lotspeich [États-Unis] ; James Sutcliffe [États-Unis] ; Jonathan Haines [États-Unis] ; Susan Folstein [États-Unis] ; Joseph Piven [États-Unis] ; Thomas Wassink [États-Unis] ; Val Sheffield [États-Unis] ; Daniel Geschwind [États-Unis] ; Maja Bucan [États-Unis] ; Ted Brown [États-Unis] ; Rita Cantor [États-Unis] ; John Constantino [États-Unis] ; Conrad Gilliam [États-Unis] ; Martha Herbert [États-Unis] ; Clara Lajonchere [États-Unis] ; David Ledbetter [États-Unis] ; Christa Lese-Martin [États-Unis] ; Janet Miller [États-Unis] ; Stan Nelson [Allemagne] ; Carol Samango-Sprouse [États-Unis] ; Sarah Spence [États-Unis] ; Matthew State [Allemagne] ; Rudolph Tanzi [France] ; Hilary Coon [Italie] ; Geraldine Dawson [États-Unis] ; Bernie Devlin [États-Unis] ; Annette Estes [États-Unis] ; Pamela Flodman [États-Unis] ; Lambertus Klei [États-Unis] ; William Mcmahon [Italie] ; Nancy Minshew [États-Unis] ; Jeff Munson [États-Unis] ; Elena Korvatska [États-Unis] ; Patricia Rodier [États-Unis] ; Gerard Schellenberg [États-Unis] ; Moyra Smith [États-Unis] ; Anne Spence [États-Unis] ; Chris Stodgell [États-Unis] ; Ping Guo Tepper [États-Unis] ; Ellen Wijsman [États-Unis] ; Chang-En Yu [États-Unis] ; Bernadette Rogé [France] ; Carine Mantoulan [France] ; Kerstin Wittemeyer [Royaume-Uni] ; Annemarie Poustka [Allemagne] ; B Rbel Felder [Allemagne] ; Sabine Klauck [Allemagne] ; Claudia Schuster [Allemagne] ; Fritz Poustka [Allemagne] ; Sven Bölte [Allemagne] ; Sabine Feineis-Matthews [Allemagne] ; Evelyn Herbrecht [Allemagne] ; Gabi Schmötzer [Allemagne] ; John Tsiantis [Grèce] ; Katerina Papanikolaou [Grèce] ; Elena Maestrini [Italie] ; Elena Bacchelli [Italie] ; Francesca Blasi [Italie] ; Simona Carone [Italie] ; Claudio Toma [Italie] ; Herman Van Engeland [Pays-Bas] ; Maretha De Jonge [Pays-Bas] ; Chantal Kemner [Pays-Bas] ; Frederieke Koop [Pays-Bas] ; Marjolein Langemeijer [Pays-Bas] ; Channa Hijmans [Pays-Bas] ; Wouter Staal [Pays-Bas] ; Gillian Baird [Royaume-Uni] ; Patrick Bolton [Royaume-Uni] ; Michael Rutter [Royaume-Uni] ; Emma Weisblatt [France] ; Jonathan Green [Royaume-Uni] ; Catherine Aldred [Royaume-Uni] ; Julie-Anne Wilkinson [Royaume-Uni] ; Andrew Pickles [Royaume-Uni] ; Ann Le Couteur [Royaume-Uni] ; Tom Berney [Royaume-Uni] ; Helen Mcconachie [Royaume-Uni] ; Anthony Bailey [Royaume-Uni] ; Kostas Francis [Royaume-Uni] ; Gemma Honeyman [Royaume-Uni] ; Aislinn Hutchinson [Royaume-Uni] ; Jeremy Parr [Royaume-Uni] ; Simon Wallace [Royaume-Uni] ; Anthony Monaco [Royaume-Uni] ; Gabrielle Barnby [Royaume-Uni] ; Kazuhiro Kobayashi [Royaume-Uni] ; Janine Lamb [Royaume-Uni] ; Ines Sousa [Royaume-Uni] ; Nuala Sykes [Royaume-Uni] ; Edwin Cook [États-Unis] ; Stephen Guter [États-Unis] ; Bennett Leventhal [États-Unis] ; Jeff Salt [États-Unis] ; Catherine Lord [États-Unis] ; Christina Corsello [États-Unis] ; Vanessa Hus [États-Unis] ; Daniel Weeks [États-Unis] ; Fred Volkmar [États-Unis] ; Maïté Tauber [France] ; Eric Fombonne [Canada] ; Andy Shih [États-Unis] ; Kacie Meyer [États-Unis]Source :
- Nature Genetics [ 1061-4036 ] ; 2007-03.
Abstract
Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions. The genetic architecture of ASDs is complex, requiring large samples to overcome heterogeneity. Here we broaden coverage and sample size relative to other studies of ASDs by using Affymetrix 10K SNP arrays and 1,181 [corrected] families with at least two affected individuals, performing the largest linkage scan to date while also analyzing copy number variation in these families. Linkage and copy number variation analyses implicate chromosome 11p12-p13 and neurexins, respectively, among other candidate loci. Neurexins team with previously implicated neuroligins for glutamatergic synaptogenesis, highlighting glutamate-related genes as promising candidates for contributing to ASDs.
Url:
DOI: 10.1038/ng1985
Affiliations:
- Allemagne, Canada, France, Grèce, Italie, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Illinois, Iowa, Missouri (État), Ontario, Pennsylvanie, Québec
- Chicago, Iowa City, Montréal, Pittsburgh, Saint-Louis (Missouri), Toronto
- Université McGill, Université Washington de Saint-Louis, Université de Pittsburgh, Université de Toronto, Université de l'Illinois à Chicago, Université de l'Iowa
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000367
- to stream Hal, to step Curation: 000367
- to stream Hal, to step Checkpoint: 000599
- to stream Main, to step Merge: 00B146
- to stream Main, to step Curation: 00A993
- to stream Main, to step Exploration: 00A993
- to stream France, to step Extraction: 000759
Links to Exploration step
Hal:inserm-00937094Le document en format XML
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<country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="State, Matthew" sort="State, Matthew" uniqKey="State M" first="Matthew" last="State">Matthew State</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-168273" status="INCOMING"> <orgName>Institute of Human Genetics</orgName> <desc> <address> <addrLine>Regina-Pacis-Weg 3, 53113 Bonn</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-300970" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300970" type="direct"><org type="institution" xml:id="struct-300970" status="VALID"> <orgName>Bonn Universität [Bonn]</orgName> <desc> <address> <addrLine>Sigmund-Freud-Straße 25, 53127 Bonn</addrLine> <country key="DE"></country> </address> <ref type="url">https://www.uni-bonn.de/news-1</ref> </desc> 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last="Coon">Hilary Coon</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128956" status="INCOMING"> <orgName>Department of Developmental Neuroscience</orgName> <desc> <address> <addrLine>Viale del Tirreno 331 - 56128, Calambrone, Pisa</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-361570" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-361570" type="direct"><org type="institution" xml:id="struct-361570" status="VALID"> <orgName>IRCCS Fondazione Stella Maris [Pisa]</orgName> <desc> <address> <addrLine>Viale del Tirreno, 331, 56128 Calambrone</addrLine> <country key="IT"></country> </address> <ref type="url">http://www.fsm.unipi.it/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Dawson, Geraldine" sort="Dawson, Geraldine" uniqKey="Dawson G" first="Geraldine" last="Dawson">Geraldine Dawson</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-173887" status="INCOMING"> <orgName>Autism Speaks and the Department of Psychiatry</orgName> <desc> <address> <addrLine>Chapel Hill, North Carolina</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-44261" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-44261" type="direct"><org type="institution" xml:id="struct-44261" status="VALID"> <orgName>The University of North Carolina at Chapel Hill</orgName> <desc> <address> <addrLine>250 East Franklin Street, Chapel Hill, NC,</addrLine> <country key="US"></country> </address> <ref type="url">http://www.unc.edu</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Devlin, Bernie" sort="Devlin, Bernie" uniqKey="Devlin B" first="Bernie" last="Devlin">Bernie Devlin</name><affiliation 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Annette" sort="Estes, Annette" uniqKey="Estes A" first="Annette" last="Estes">Annette Estes</name><affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-128937" status="VALID"> <orgName>Department of Speech and Hearing Sciences [Washington]</orgName> <desc> <address> <addrLine>University of Washington, Seattle, WA 98195, USA</addrLine> <country key="US"></country> </address> <ref type="url">https://sphsc.washington.edu/</ref> </desc> <listRelation> <relation active="#struct-300433" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300433" type="direct"><org type="institution" xml:id="struct-300433" status="VALID"> <orgName>University of Washington [Seattle]</orgName> <desc> <address> <addrLine>Seattle, Washington 98105</addrLine> <country key="US"></country> </address> <ref type="url">http://www.washington.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name 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100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Hijmans, Channa" sort="Hijmans, Channa" uniqKey="Hijmans C" first="Channa" last="Hijmans">Channa Hijmans</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Staal, Wouter" 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</org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Baird, Gillian" sort="Baird, Gillian" uniqKey="Baird G" first="Gillian" last="Baird">Gillian Baird</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128882" status="INCOMING"> <orgName>Newcomen Centre</orgName> <desc> <address> <addrLine>London, SE1 9RT</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-154945" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-154945" type="direct"><org type="institution" xml:id="struct-154945" status="VALID"> <orgName>Guy's Hospital [London]</orgName> <desc> <address> <addrLine>Great Maze Pond London SE1 9RT</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.guysandstthomas.nhs.uk/Home.aspx</ref> </desc> 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uniqKey="Rutter M" first="Michael" last="Rutter">Michael Rutter</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-131765" status="INCOMING"> <orgName>MRC Social, Genetic and Developmental Psychiatry Centre</orgName> <orgName type="acronym">SGDP</orgName> <desc> <address> <addrLine>Strand, London WC2R 2LS</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-356202" type="direct"></relation> <relation active="#struct-327716" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-356202" type="direct"><org type="institution" xml:id="struct-356202" status="INCOMING"> <orgName>The Institute of Psychiatry</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-327716" type="direct"><org type="institution" xml:id="struct-327716" status="VALID"> <orgName>King‘s College London [London]</orgName> <desc> <address> <addrLine>Strand Campus, London WC2R 2LS</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.kcl.ac.uk</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Weisblatt, Emma" sort="Weisblatt, Emma" uniqKey="Weisblatt E" first="Emma" last="Weisblatt">Emma Weisblatt</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-242597" status="INCOMING"> <orgName>University of Cambridge Clinical School</orgName> <desc> <address> <addrLine>Cambridge</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-237843" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-237843" type="direct"><org type="institution" xml:id="struct-237843" status="VALID"> <orgName>University of Cambridge [UK]</orgName> <orgName type="acronym">CAM</orgName> <desc> <address> <addrLine>The Old Schools, Trinity Lane, Cambridge CB2 1TN</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.cam.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Green, Jonathan" sort="Green, Jonathan" uniqKey="Green J" first="Jonathan" last="Green">Jonathan Green</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112882" status="INCOMING"> <orgName>Manchester Academic Health Sciences Centre</orgName> <desc> <address> <addrLine>Manchester M13 9NT</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-342593" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-342593" type="direct"><org type="institution" xml:id="struct-342593" status="INCOMING"> <orgName>Manchester Academic Health Sciences Centre</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Aldred, Catherine" sort="Aldred, Catherine" uniqKey="Aldred C" first="Catherine" last="Aldred">Catherine Aldred</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112882" status="INCOMING"> <orgName>Manchester Academic Health Sciences Centre</orgName> <desc> <address> <addrLine>Manchester M13 9NT</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-342593" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-342593" type="direct"><org type="institution" xml:id="struct-342593" status="INCOMING"> <orgName>Manchester Academic Health Sciences Centre</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Wilkinson, Julie Anne" 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</desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Le Couteur, Ann" sort="Le Couteur, Ann" uniqKey="Le Couteur A" first="Ann" last="Le Couteur">Ann Le Couteur</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-150253" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry</orgName> <desc> <address> <addrLine>3rd Floor - Sir James Spence Institute - Royal Victoria Infirmary - Queen Victoria Road - Newcastle upon Tyne NE1 4LP</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-252912" type="direct"></relation> <relation active="#struct-360566" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-252912" type="direct"><org type="institution" xml:id="struct-252912" status="VALID"> <orgName>Newcastle University [Newcastle]</orgName> <desc> <address> <addrLine>Newcastle upon Tyne NE1 7RU</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ncl.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-360566" type="direct"><org type="institution" xml:id="struct-360566" status="INCOMING"> <orgName>Institute of Health & Society (Child & Adolescent Psychiatry)</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Berney, Tom" sort="Berney, Tom" uniqKey="Berney T" first="Tom" last="Berney">Tom Berney</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-150253" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry</orgName> <desc> <address> <addrLine>3rd Floor - Sir James Spence Institute - Royal Victoria Infirmary - Queen Victoria Road - Newcastle upon Tyne NE1 4LP</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation 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wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128883" status="INCOMING"> <orgName>Child and Adolescent Mental Health</orgName> <desc> <address> <addrLine>Sir James Spence Institute, Newcastle upon Tyne, NE1 4LP</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-252912" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-252912" type="direct"><org type="institution" xml:id="struct-252912" status="VALID"> <orgName>Newcastle University [Newcastle]</orgName> <desc> <address> <addrLine>Newcastle upon Tyne NE1 7RU</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ncl.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Bailey, Anthony" sort="Bailey, Anthony" uniqKey="Bailey A" first="Anthony" last="Bailey">Anthony Bailey</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128881" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Headington, Oxford, OX3 7JX</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> <relation active="#struct-322847" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-322847" type="direct"><org type="institution" xml:id="struct-322847" status="INCOMING"> <orgName>Warneford Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Francis, Kostas" sort="Francis, Kostas" uniqKey="Francis K" first="Kostas" last="Francis">Kostas Francis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128881" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Headington, Oxford, OX3 7JX</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> <relation active="#struct-322847" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-322847" type="direct"><org type="institution" xml:id="struct-322847" status="INCOMING"> <orgName>Warneford Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Honeyman, Gemma" sort="Honeyman, Gemma" uniqKey="Honeyman G" first="Gemma" last="Honeyman">Gemma Honeyman</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128881" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Headington, Oxford, OX3 7JX</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> <relation active="#struct-322847" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-322847" type="direct"><org type="institution" xml:id="struct-322847" status="INCOMING"> <orgName>Warneford Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Hutchinson, Aislinn" sort="Hutchinson, Aislinn" uniqKey="Hutchinson A" first="Aislinn" last="Hutchinson">Aislinn Hutchinson</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128881" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Headington, Oxford, OX3 7JX</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> <relation active="#struct-322847" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-322847" type="direct"><org type="institution" xml:id="struct-322847" status="INCOMING"> <orgName>Warneford Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Parr, Jeremy" sort="Parr, Jeremy" uniqKey="Parr J" first="Jeremy" last="Parr">Jeremy Parr</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128881" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Headington, Oxford, OX3 7JX</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> <relation active="#struct-322847" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-322847" type="direct"><org type="institution" xml:id="struct-322847" status="INCOMING"> <orgName>Warneford Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> 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<desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Barnby, Gabrielle" sort="Barnby, Gabrielle" uniqKey="Barnby G" first="Gabrielle" last="Barnby">Gabrielle Barnby</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128858" status="INCOMING"> <orgName>Wellcome Trust Centre for Human Genetics</orgName> <desc> <address> <addrLine>Roosevelt Drive - Headington, Oxford OX3 7BN</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington 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2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Lamb, Janine" sort="Lamb, Janine" uniqKey="Lamb J" first="Janine" last="Lamb">Janine Lamb</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128858" status="INCOMING"> <orgName>Wellcome Trust Centre for Human Genetics</orgName> <desc> <address> <addrLine>Roosevelt Drive - Headington, Oxford OX3 7BN</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref 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Chicago</orgName></affiliation></author><author><name sortKey="Leventhal, Bennett" sort="Leventhal, Bennett" uniqKey="Leventhal B" first="Bennett" last="Leventhal">Bennett Leventhal</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-200668" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry</orgName> <desc> <address> <addrLine>NYU Child Study Center - 70 Washington Square S, New York, NY 10012</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-300459" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300459" type="direct"><org type="institution" xml:id="struct-300459" status="VALID"> <orgName>New York University [New York]</orgName> <desc> <address> <addrLine>70 Washington Square South, New York, NY 10012</addrLine> <country key="US"></country> </address> <ref type="url">http://www.nyu.edu/</ref> </desc> 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<country key="US"></country> </address> <ref type="url">http://www.pitt.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Lord, Catherine" sort="Lord, Catherine" uniqKey="Lord C" first="Catherine" last="Lord">Catherine Lord</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128932" status="INCOMING"> <orgName>Autism and Communicative Disorders Centre</orgName> <desc> <address> <addrLine>Ann Arbor, Michigan</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-24332" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-24332" type="direct"><org type="institution" xml:id="struct-24332" status="VALID"> <orgName>University of Michigan [Ann Arbor]</orgName> <desc> <address> <addrLine>500 Church Street Ann Arbor, MI 48109-1090</addrLine> <country key="US"></country> </address> <ref type="url">http://www.umich.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Corsello, Christina" sort="Corsello, Christina" uniqKey="Corsello C" first="Christina" last="Corsello">Christina Corsello</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128932" status="INCOMING"> <orgName>Autism and Communicative Disorders Centre</orgName> <desc> <address> <addrLine>Ann Arbor, Michigan</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-24332" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-24332" type="direct"><org type="institution" xml:id="struct-24332" status="VALID"> <orgName>University of Michigan [Ann Arbor]</orgName> <desc> <address> <addrLine>500 Church Street Ann Arbor, MI 48109-1090</addrLine> <country key="US"></country> </address> <ref type="url">http://www.umich.edu/</ref> 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</org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Weeks, Daniel" sort="Weeks, Daniel" uniqKey="Weeks D" first="Daniel" last="Weeks">Daniel Weeks</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-142567" status="INCOMING"> <orgName>Human Genetics Department</orgName> <desc> <address> <addrLine>4200 Fifth Ave, Pittsburgh, PA 15260</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-378064" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-378064" type="direct"><org type="institution" xml:id="struct-378064" status="INCOMING"> <orgName>University of Pittsburgh</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Volkmar, Fred" sort="Volkmar, Fred" uniqKey="Volkmar F" first="Fred" last="Volkmar">Fred Volkmar</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128985" status="INCOMING"> <orgName>Child Study Centre</orgName> <desc> <address> <addrLine>New Haven, Connecticut 0652</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-300737" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300737" type="direct"><org type="institution" xml:id="struct-300737" status="VALID"> <orgName>Yale School of Medicine</orgName> <desc> <address> <addrLine>333 Cedar Street New Haven CT 06510</addrLine> <country key="US"></country> </address> <ref type="url">http://medicine.yale.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Tauber, Maite" sort="Tauber, Maite" uniqKey="Tauber M" first="Maïté" last="Tauber">Maïté Tauber</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-207731" status="INCOMING"> <orgName>Centre d'Endocrinologie, Maladies Osseuses, Génétique et Gynécologie Médicale</orgName> <desc> <address> <addrLine>330, avenue de Grande-Bretagne - TSA 70034 - 31059 Toulouse cedex 9</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300075" type="direct"></relation> <relation active="#struct-307239" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300075" type="direct"><org type="institution" xml:id="struct-300075" status="VALID"> <orgName>CHU Toulouse [Toulouse]</orgName> <desc> <address> <addrLine>330 Avenue de Grande Bretagne, TSA 40031, 31059 Toulouse Cedex 09</addrLine> <country key="FR"></country> </address> </desc></org></tutelle><tutelle active="#struct-307239" type="direct"><org type="institution" xml:id="struct-307239" status="INCOMING"> <orgName>Hôpital des Enfants</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Fombonne, Eric" sort="Fombonne, Eric" uniqKey="Fombonne E" first="Eric" last="Fombonne">Eric Fombonne</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-129063" status="INCOMING"> <orgName>Department of Child Psychiatry</orgName> <desc> <address> <addrLine>2300 rue Tupper, Montreal, H3H 1P3</addrLine> <country key="CA"></country> </address> </desc> <listRelation> <relation active="#struct-134741" type="direct"></relation> <relation active="#struct-312535" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-134741" type="direct"><org type="institution" xml:id="struct-134741" status="VALID"> <orgName>McGill University</orgName> <desc> <address> <addrLine>845, rue Sherbrooke O. Montréal (Québec) Canada H3A 0G4</addrLine> <country key="CA"></country> </address> <ref type="url">http://www.mcgill.ca/</ref> </desc> </org></tutelle><tutelle active="#struct-312535" type="direct"><org type="institution" xml:id="struct-312535" status="INCOMING"> <orgName>Montreal Children's Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Shih, Andy" sort="Shih, Andy" uniqKey="Shih A" first="Andy" last="Shih">Andy Shih</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128935" status="INCOMING"> <orgName>Scientific Affairs</orgName> <desc> <address> <addrLine>2 Park Avenue, 11th Floor, New York, NY 10016</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-331243" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-331243" type="direct"><org type="institution" xml:id="struct-331243" status="INCOMING"> <orgName>Autism Speaks</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Meyer, Kacie" sort="Meyer, Kacie" uniqKey="Meyer K" first="Kacie" last="Meyer">Kacie Meyer</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-183914" status="VALID"> <orgName>University of Iowa [Iowa]</orgName> <desc> <address> <addrLine>Iowa City, IA 52242</addrLine> <country key="US"></country> </address> </desc> </hal:affiliation><country>États-Unis</country></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:inserm-00937094</idno><idno type="halId">inserm-00937094</idno><idno type="halUri">http://www.hal.inserm.fr/inserm-00937094</idno><idno type="url">http://www.hal.inserm.fr/inserm-00937094</idno><idno type="doi">10.1038/ng1985</idno><date when="2007-03">2007-03</date><idno type="wicri:Area/Hal/Corpus">000367</idno><idno type="wicri:Area/Hal/Curation">000367</idno><idno type="wicri:Area/Hal/Checkpoint">000599</idno><idno type="wicri:explorRef" wicri:stream="Hal" wicri:step="Checkpoint">000599</idno><idno type="wicri:doubleKey">1061-4036:2007:Szatmari P:mapping:autism:risk</idno><idno type="wicri:Area/Main/Merge">00B146</idno><idno type="wicri:Area/Main/Curation">00A993</idno><idno type="wicri:Area/Main/Exploration">00A993</idno><idno type="wicri:Area/France/Extraction">000759</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Mapping autism risk loci using genetic linkage and chromosomal rearrangements.</title><author><name sortKey="Szatmari, Peter" sort="Szatmari, Peter" uniqKey="Szatmari P" first="Peter" last="Szatmari">Peter Szatmari</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-142518" status="INCOMING"> <orgName>Department of Psychiatry and Behavioural Neurosciences</orgName> <desc> <address> <addrLine>Hamilton, Ontario, L8S 4K1</addrLine> <country key="CA"></country> </address> </desc> <listRelation> <relation active="#struct-64587" type="direct"></relation> <relation active="#struct-361531" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-64587" type="direct"><org type="institution" xml:id="struct-64587" status="VALID"> <orgName>McMaster University [Hamilton, Ontario]</orgName> <desc> <address> <addrLine>1280 Main Street WestHamilton, Ontario L8S 4L8</addrLine> <country key="CA"></country> </address> <ref type="url">http://www.mcmaster.ca/</ref> </desc> </org></tutelle><tutelle active="#struct-361531" type="direct"><org type="institution" xml:id="struct-361531" status="INCOMING"> 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xml:id="struct-300722" status="VALID"> <orgName>University of Toronto</orgName> <desc> <address> <addrLine>27 King's College Circle, Toronto M5S 1A1</addrLine> <country key="CA"></country> </address> <ref type="url">http://www.utoronto.ca/</ref> </desc> </org></tutelle><tutelle active="#struct-305187" type="direct"><org type="institution" xml:id="struct-305187" status="INCOMING"> <orgName>The Hospital for Sick Children</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-322377" type="direct"><org type="institution" xml:id="struct-322377" status="INCOMING"> <orgName>Department of Molecular Genetics</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-339724" type="direct"><org type="institution" xml:id="struct-339724" status="INCOMING"> <orgName>McLaughlin Centre</orgName> <desc> <address> <country key="FR"></country> </address> </desc> 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[Hamilton, Ontario]</orgName> <desc> <address> <addrLine>1280 Main Street WestHamilton, Ontario L8S 4L8</addrLine> <country key="CA"></country> </address> <ref type="url">http://www.mcmaster.ca/</ref> </desc> </org></tutelle><tutelle active="#struct-361531" type="direct"><org type="institution" xml:id="struct-361531" status="INCOMING"> <orgName>Offord Centre for Child Studies</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Canada</country></affiliation></author><author><name sortKey="Senman, Lili" sort="Senman, Lili" uniqKey="Senman L" first="Lili" last="Senman">Lili Senman</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128885" status="INCOMING"> <orgName>Autism Research Unit</orgName> <desc> <address> <addrLine>Toronto, Ontario, M5G 1X8</addrLine> <country key="CA"></country> </address> </desc> <listRelation> <relation active="#struct-300722" type="direct"></relation> 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<addrLine>University of North Carolina Chapel Hill Campus Box # 7255 Chapel Hill, N.C. 27599-3366</addrLine> <country key="US"></country> </address> <ref type="url">http://www.cidd.unc.edu/</ref> </desc> <listRelation> <relation active="#struct-44261" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-44261" type="direct"><org type="institution" xml:id="struct-44261" status="VALID"> <orgName>The University of North Carolina at Chapel Hill</orgName> <desc> <address> <addrLine>250 East Franklin Street, Chapel Hill, NC,</addrLine> <country key="US"></country> </address> <ref type="url">http://www.unc.edu</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Wassink, Thomas" sort="Wassink, Thomas" uniqKey="Wassink T" first="Thomas" last="Wassink">Thomas Wassink</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128986" status="INCOMING"> 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Levi Hall 5801 South Ellis Avenue Chicago, Illinois 60637</addrLine><country key="US"></country></address><ref type="url">http://www.uchicago.edu/</ref></desc></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Herbert, Martha" sort="Herbert, Martha" uniqKey="Herbert M" first="Martha" last="Herbert">Martha Herbert</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-242589" status="INCOMING"> <orgName>Harvard Medical School</orgName> <desc> <address> <addrLine>Boston, MA</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-161455" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-161455" type="direct"><org type="institution" xml:id="struct-161455" status="VALID"> <orgName>Massachusetts General Hospital [Boston]</orgName> <orgName type="acronym">MGH</orgName> <desc> <address> <addrLine>Massachusetts General Hospital 55 Fruit Street Boston, MA 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</org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Lese Martin, Christa" sort="Lese Martin, Christa" uniqKey="Lese Martin C" first="Christa" last="Lese-Martin">Christa Lese-Martin</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-242590" status="INCOMING"> <orgName>Department of Genetics</orgName> <desc> <address> <addrLine>Atlanta, GA</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-301506" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-301506" type="direct"><org type="institution" xml:id="struct-301506" status="VALID"> <orgName>Emory University [Atlanta, GA]</orgName> <desc> <address> <addrLine>201 Dowman Dr, Atlanta, GA 30322</addrLine> <country key="US"></country> </address> <ref type="url">http://www.emory.edu</ref> </desc> 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wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-27601" status="INCOMING"> <orgName>Children's National Medical Center</orgName> <desc> <address> <addrLine>School of Medicine - 2121 I St NW, Washington, DC 20052</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-304728" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-304728" type="direct"><org type="institution" xml:id="struct-304728" status="VALID"> <orgName>George Washington University</orgName> <orgName type="acronym">GW</orgName> <desc> <address> <addrLine>2121 Eye Street, NW , Washington, DC 20052 </addrLine> <country key="US"></country> </address> <ref type="url">https://www.gwu.edu</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Spence, Sarah" sort="Spence, Sarah" uniqKey="Spence S" first="Sarah" last="Spence">Sarah Spence</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-191541" status="INCOMING"> <orgName>Department of Human Genetics, UCLA</orgName> <desc> <address> <addrLine>David Geffen School of Medicine, CA 90095</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-72398" type="direct"></relation> <relation active="#struct-339234" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-72398" type="direct"><org type="institution" xml:id="struct-72398" status="VALID"> <orgName>University of California at Los Angeles [Los Angeles]</orgName> <orgName type="acronym">UCLA</orgName> <desc> <address> <addrLine> Los Angeles, Californie 90095</addrLine> <country key="US"></country> </address> <ref type="url">http://www.ucla.edu/</ref> </desc> </org></tutelle><tutelle active="#struct-339234" type="direct"><org type="institution" xml:id="struct-339234" status="INCOMING"> <orgName>Semel Institute</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="State, Matthew" sort="State, Matthew" uniqKey="State M" first="Matthew" last="State">Matthew State</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-168273" status="INCOMING"> <orgName>Institute of Human Genetics</orgName> <desc> <address> <addrLine>Regina-Pacis-Weg 3, 53113 Bonn</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-300970" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300970" type="direct"><org type="institution" xml:id="struct-300970" status="VALID"> <orgName>Bonn Universität [Bonn]</orgName> <desc> <address> <addrLine>Sigmund-Freud-Straße 25, 53127 Bonn</addrLine> <country key="DE"></country> </address> <ref type="url">https://www.uni-bonn.de/news-1</ref> </desc> 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last="Coon">Hilary Coon</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128956" status="INCOMING"> <orgName>Department of Developmental Neuroscience</orgName> <desc> <address> <addrLine>Viale del Tirreno 331 - 56128, Calambrone, Pisa</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-361570" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-361570" type="direct"><org type="institution" xml:id="struct-361570" status="VALID"> <orgName>IRCCS Fondazione Stella Maris [Pisa]</orgName> <desc> <address> <addrLine>Viale del Tirreno, 331, 56128 Calambrone</addrLine> <country key="IT"></country> </address> <ref type="url">http://www.fsm.unipi.it/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Dawson, Geraldine" sort="Dawson, Geraldine" uniqKey="Dawson G" first="Geraldine" last="Dawson">Geraldine 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Annette" sort="Estes, Annette" uniqKey="Estes A" first="Annette" last="Estes">Annette Estes</name><affiliation wicri:level="1"><hal:affiliation type="department" xml:id="struct-128937" status="VALID"> <orgName>Department of Speech and Hearing Sciences [Washington]</orgName> <desc> <address> <addrLine>University of Washington, Seattle, WA 98195, USA</addrLine> <country key="US"></country> </address> <ref type="url">https://sphsc.washington.edu/</ref> </desc> <listRelation> <relation active="#struct-300433" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300433" type="direct"><org type="institution" xml:id="struct-300433" status="VALID"> <orgName>University of Washington [Seattle]</orgName> <desc> <address> <addrLine>Seattle, Washington 98105</addrLine> <country key="US"></country> </address> <ref type="url">http://www.washington.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Flodman, Pamela" sort="Flodman, Pamela" uniqKey="Flodman P" first="Pamela" last="Flodman">Pamela Flodman</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-242593" status="INCOMING"> <orgName>Department of Pediatrics</orgName> <desc> <address> <addrLine>Irvine, CA 92697</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-445806" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-445806" type="direct"><org type="institution" xml:id="struct-445806" status="VALID"> <orgName>University of California [Irvine]</orgName> <orgName type="acronym">UCI</orgName> <desc> <address> <addrLine>Irvine, CA 92697</addrLine> <country key="US"></country> </address> <ref type="url">https://uci.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Klei, Lambertus" sort="Klei, Lambertus" uniqKey="Klei L" 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15260</addrLine> <country key="US"></country> </address> <ref type="url">http://www.pitt.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Munson, Jeff" sort="Munson, Jeff" uniqKey="Munson J" first="Jeff" last="Munson">Jeff Munson</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-129064" status="INCOMING"> <orgName>Department of Psychiatry and Behavioral Sciences</orgName> <desc> <address> <addrLine>Seattle, WA 98195</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-300433" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300433" type="direct"><org type="institution" xml:id="struct-300433" status="VALID"> <orgName>University of Washington [Seattle]</orgName> <desc> <address> <addrLine>Seattle, Washington 98105</addrLine> <country key="US"></country> </address> <ref type="url">http://www.washington.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Korvatska, Elena" sort="Korvatska, Elena" uniqKey="Korvatska E" first="Elena" last="Korvatska">Elena Korvatska</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-242593" status="INCOMING"> <orgName>Department of Pediatrics</orgName> <desc> <address> <addrLine>Irvine, CA 92697</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-445806" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-445806" type="direct"><org type="institution" xml:id="struct-445806" status="VALID"> <orgName>University of California [Irvine]</orgName> <orgName type="acronym">UCI</orgName> <desc> <address> <addrLine>Irvine, CA 92697</addrLine> <country key="US"></country> </address> <ref type="url">https://uci.edu/</ref> </desc> 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<address> <addrLine>Université Toulouse - Jean Jaurès (campus Mirail), Maison de la Recherche 5, Allées A. Machado 31058 Toulouse Cedex 9</addrLine> <country key="FR"></country> </address> <ref type="url">http://w3.octogone.univ-tlse2.fr</ref> </desc> <listRelation> <relation name="EA4156" active="#struct-116256" type="direct"></relation> </listRelation> <tutelles><tutelle name="EA4156" active="#struct-116256" type="direct"><org type="institution" xml:id="struct-116256" status="VALID"> <idno type="IdRef">026403994</idno> <orgName>Université Toulouse 2</orgName> <orgName type="acronym">UT2</orgName> <date type="start">1971-01-01</date> <desc> <address> <addrLine>5 allées Antonio Machado - 31058 Toulouse Cedex 9 </addrLine> <country key="FR"></country> </address> <ref type="url">http://www.univ-tlse2.fr</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Mantoulan, Carine" sort="Mantoulan, Carine" uniqKey="Mantoulan C" first="Carine" last="Mantoulan">Carine Mantoulan</name><affiliation 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<addrLine>Senckenberganlage 31 - 60325 Frankfurt am Main</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-302435" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302435" type="direct"><org type="institution" xml:id="struct-302435" status="VALID"> <orgName>Goethe-Universität Frankfurt am Main</orgName> <desc> <address> <addrLine>Theodor-W.-Adorno-Platz 1 , 60323 Frankfurt am Main</addrLine> <country key="DE"></country> </address> <ref type="url">http://www.goethe-university-frankfurt.de/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Allemagne</country></affiliation></author><author><name sortKey="Herbrecht, Evelyn" sort="Herbrecht, Evelyn" uniqKey="Herbrecht E" first="Evelyn" last="Herbrecht">Evelyn Herbrecht</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112863" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy</orgName> <desc> <address> <addrLine>Senckenberganlage 31 - 60325 Frankfurt am Main</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-302435" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302435" type="direct"><org type="institution" xml:id="struct-302435" status="VALID"> <orgName>Goethe-Universität Frankfurt am Main</orgName> <desc> <address> <addrLine>Theodor-W.-Adorno-Platz 1 , 60323 Frankfurt am Main</addrLine> <country key="DE"></country> </address> <ref type="url">http://www.goethe-university-frankfurt.de/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Allemagne</country></affiliation></author><author><name sortKey="Schmotzer, Gabi" sort="Schmotzer, Gabi" uniqKey="Schmotzer G" first="Gabi" last="Schmötzer">Gabi Schmötzer</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112863" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy</orgName> <desc> <address> <addrLine>Senckenberganlage 31 - 60325 Frankfurt am Main</addrLine> <country key="DE"></country> </address> </desc> <listRelation> <relation active="#struct-302435" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302435" type="direct"><org type="institution" xml:id="struct-302435" status="VALID"> <orgName>Goethe-Universität Frankfurt am Main</orgName> <desc> <address> <addrLine>Theodor-W.-Adorno-Platz 1 , 60323 Frankfurt am Main</addrLine> <country key="DE"></country> </address> <ref type="url">http://www.goethe-university-frankfurt.de/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Allemagne</country></affiliation></author><author><name sortKey="Tsiantis, John" sort="Tsiantis, John" uniqKey="Tsiantis J" first="John" last="Tsiantis">John Tsiantis</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112872" status="INCOMING"> <orgName>University Department of Child Psychiatry</orgName> <desc> <address> <addrLine>Medical School, Agia Sophia Children's Hospital, 115 27 Athens</addrLine> <country key="GR"></country> </address> </desc> <listRelation> <relation active="#struct-35091" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-35091" type="direct"><org type="institution" xml:id="struct-35091" status="VALID"> <orgName>University of Athens</orgName> <orgName type="acronym">UoA</orgName> <desc> <address> <addrLine>Zografou Campus, GR-157 80 Zografou</addrLine> <country key="GR"></country> </address> <ref type="url">http://uoa.gr/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Grèce</country></affiliation></author><author><name sortKey="Papanikolaou, Katerina" sort="Papanikolaou, Katerina" uniqKey="Papanikolaou K" first="Katerina" last="Papanikolaou">Katerina Papanikolaou</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112872" status="INCOMING"> <orgName>University Department of Child Psychiatry</orgName> <desc> <address> <addrLine>Medical School, Agia Sophia Children's Hospital, 115 27 Athens</addrLine> <country key="GR"></country> </address> </desc> <listRelation> <relation active="#struct-35091" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-35091" type="direct"><org type="institution" xml:id="struct-35091" status="VALID"> <orgName>University of Athens</orgName> <orgName type="acronym">UoA</orgName> <desc> <address> <addrLine>Zografou Campus, GR-157 80 Zografou</addrLine> <country key="GR"></country> </address> <ref type="url">http://uoa.gr/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Grèce</country></affiliation></author><author><name sortKey="Maestrini, Elena" sort="Maestrini, Elena" uniqKey="Maestrini E" first="Elena" last="Maestrini">Elena Maestrini</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-57919" status="INCOMING"> <orgName>Department of Pharmacy and Biotechnology</orgName> <desc> <address> <addrLine>Via Zamboni, 33, 40126 Bologna</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-30978" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-30978" type="direct"><org type="institution" xml:id="struct-30978" status="VALID"> <orgName>Università di Bologna [Bologna]</orgName> <orgName type="acronym">UNIBO</orgName> <desc> <address> <addrLine>Via Zamboni, 33 - 40126 Bologna</addrLine> <country key="IT"></country> </address> <ref type="url">http://www.eng.unibo.it/PortaleEn/default.htm</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Bacchelli, Elena" sort="Bacchelli, Elena" uniqKey="Bacchelli E" first="Elena" last="Bacchelli">Elena Bacchelli</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-57919" status="INCOMING"> <orgName>Department of Pharmacy and Biotechnology</orgName> <desc> <address> <addrLine>Via Zamboni, 33, 40126 Bologna</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-30978" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-30978" type="direct"><org type="institution" xml:id="struct-30978" status="VALID"> <orgName>Università di Bologna [Bologna]</orgName> <orgName type="acronym">UNIBO</orgName> <desc> <address> <addrLine>Via Zamboni, 33 - 40126 Bologna</addrLine> <country key="IT"></country> </address> <ref type="url">http://www.eng.unibo.it/PortaleEn/default.htm</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Blasi, Francesca" sort="Blasi, Francesca" uniqKey="Blasi F" first="Francesca" last="Blasi">Francesca Blasi</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-57919" status="INCOMING"> <orgName>Department of Pharmacy and Biotechnology</orgName> <desc> <address> <addrLine>Via Zamboni, 33, 40126 Bologna</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-30978" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-30978" type="direct"><org type="institution" xml:id="struct-30978" status="VALID"> <orgName>Università di Bologna [Bologna]</orgName> <orgName type="acronym">UNIBO</orgName> <desc> <address> <addrLine>Via Zamboni, 33 - 40126 Bologna</addrLine> <country key="IT"></country> </address> <ref type="url">http://www.eng.unibo.it/PortaleEn/default.htm</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Carone, Simona" sort="Carone, Simona" uniqKey="Carone S" first="Simona" last="Carone">Simona Carone</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-57920" status="INCOMING"> <orgName>Medical Genetics Laboratory</orgName> <desc> <address> <addrLine>Via Pietro Albertoni, 15, 40138 Bologna</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-313580" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-313580" type="direct"><org type="institution" xml:id="struct-313580" status="INCOMING"> <orgName>Policlinico S. Orsola-Malpighi</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Toma, Claudio" sort="Toma, Claudio" uniqKey="Toma C" first="Claudio" last="Toma">Claudio Toma</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-57919" status="INCOMING"> <orgName>Department of Pharmacy and Biotechnology</orgName> <desc> <address> <addrLine>Via Zamboni, 33, 40126 Bologna</addrLine> <country key="IT"></country> </address> </desc> <listRelation> <relation active="#struct-30978" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-30978" type="direct"><org type="institution" xml:id="struct-30978" status="VALID"> <orgName>Università di Bologna [Bologna]</orgName> <orgName type="acronym">UNIBO</orgName> <desc> <address> <addrLine>Via Zamboni, 33 - 40126 Bologna</addrLine> <country key="IT"></country> </address> <ref type="url">http://www.eng.unibo.it/PortaleEn/default.htm</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Italie</country></affiliation></author><author><name sortKey="Van Engeland, Herman" sort="Van Engeland, Herman" uniqKey="Van Engeland H" first="Herman" last="Van Engeland">Herman Van Engeland</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="De Jonge, Maretha" sort="De Jonge, Maretha" uniqKey="De Jonge M" first="Maretha" last="De Jonge">Maretha De Jonge</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Kemner, Chantal" sort="Kemner, Chantal" uniqKey="Kemner C" first="Chantal" last="Kemner">Chantal Kemner</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-112799" status="INCOMING"> <orgName>Department of Neurocognition</orgName> <desc> <address> <addrLine>Faculty of Psychology - Minderbroedersberg 4, 6211 LK Maastricht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-83832" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-83832" type="direct"><org type="institution" xml:id="struct-83832" status="VALID"> <orgName>Maastricht University [Maastricht]</orgName> <desc> <address> <addrLine>Universiteitssingel 40;6200 MD Maastricht</addrLine> <country key="NL"></country> </address> <ref type="url">http://www.maastrichtuniversity.nl/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Koop, Frederieke" sort="Koop, Frederieke" uniqKey="Koop F" first="Frederieke" last="Koop">Frederieke Koop</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Langemeijer, Marjolein" sort="Langemeijer, Marjolein" uniqKey="Langemeijer M" first="Marjolein" last="Langemeijer">Marjolein Langemeijer</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Hijmans, Channa" sort="Hijmans, Channa" uniqKey="Hijmans C" first="Channa" last="Hijmans">Channa Hijmans</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Staal, Wouter" sort="Staal, Wouter" uniqKey="Staal W" first="Wouter" last="Staal">Wouter Staal</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128605" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Heidelberglaan 100, 3584 CX Utrecht</addrLine> <country key="NL"></country> </address> </desc> <listRelation> <relation active="#struct-309434" type="direct"></relation> <relation active="#struct-361530" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309434" type="direct"><org type="institution" xml:id="struct-309434" status="INCOMING"> <orgName>University Medical Center Utrecht</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-361530" type="direct"><org type="institution" xml:id="struct-361530" status="INCOMING"> <orgName>Brain Center Rudolf Magnus</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Pays-Bas</country></affiliation></author><author><name sortKey="Baird, Gillian" sort="Baird, Gillian" uniqKey="Baird G" first="Gillian" last="Baird">Gillian Baird</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128882" status="INCOMING"> <orgName>Newcomen Centre</orgName> <desc> <address> <addrLine>London, SE1 9RT</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-154945" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-154945" type="direct"><org type="institution" xml:id="struct-154945" status="VALID"> <orgName>Guy's Hospital [London]</orgName> <desc> <address> <addrLine>Great Maze Pond London SE1 9RT</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.guysandstthomas.nhs.uk/Home.aspx</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Bolton, Patrick" sort="Bolton, Patrick" uniqKey="Bolton P" first="Patrick" last="Bolton">Patrick Bolton</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128884" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry</orgName> <desc> <address> <addrLine>London, SE5 8AF</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-311910" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-311910" type="direct"><org type="institution" xml:id="struct-311910" status="INCOMING"> <orgName>Institute of psychiatry</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Rutter, Michael" sort="Rutter, Michael" uniqKey="Rutter M" first="Michael" last="Rutter">Michael Rutter</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-131765" status="INCOMING"> <orgName>MRC Social, Genetic and Developmental Psychiatry Centre</orgName> <orgName type="acronym">SGDP</orgName> <desc> <address> <addrLine>Strand, London WC2R 2LS</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-356202" type="direct"></relation> <relation active="#struct-327716" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-356202" type="direct"><org type="institution" xml:id="struct-356202" status="INCOMING"> <orgName>The Institute of Psychiatry</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle><tutelle active="#struct-327716" type="direct"><org type="institution" xml:id="struct-327716" status="VALID"> <orgName>King‘s College London [London]</orgName> <desc> <address> <addrLine>Strand Campus, London WC2R 2LS</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.kcl.ac.uk</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Weisblatt, Emma" sort="Weisblatt, Emma" uniqKey="Weisblatt E" first="Emma" last="Weisblatt">Emma Weisblatt</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-242597" status="INCOMING"> <orgName>University of Cambridge Clinical School</orgName> <desc> <address> <addrLine>Cambridge</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-237843" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-237843" type="direct"><org type="institution" xml:id="struct-237843" status="VALID"> <orgName>University of Cambridge [UK]</orgName> <orgName type="acronym">CAM</orgName> <desc> <address> <addrLine>The Old Schools, Trinity Lane, Cambridge CB2 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7RU</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ncl.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-360566" type="direct"><org type="institution" xml:id="struct-360566" status="INCOMING"> <orgName>Institute of Health & Society (Child & Adolescent Psychiatry)</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Berney, Tom" sort="Berney, Tom" uniqKey="Berney T" first="Tom" last="Berney">Tom Berney</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-150253" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry</orgName> <desc> <address> <addrLine>3rd Floor - Sir James Spence Institute - Royal Victoria Infirmary - Queen Victoria Road - Newcastle upon Tyne NE1 4LP</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation 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<orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle><tutelle active="#struct-322847" type="direct"><org type="institution" xml:id="struct-322847" status="INCOMING"> <orgName>Warneford Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Hutchinson, Aislinn" sort="Hutchinson, Aislinn" uniqKey="Hutchinson A" first="Aislinn" last="Hutchinson">Aislinn Hutchinson</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128881" status="INCOMING"> <orgName>Department of Psychiatry</orgName> <desc> <address> <addrLine>Headington, Oxford, OX3 7JX</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation 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<desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Barnby, Gabrielle" sort="Barnby, Gabrielle" uniqKey="Barnby G" first="Gabrielle" last="Barnby">Gabrielle Barnby</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128858" status="INCOMING"> <orgName>Wellcome Trust Centre for Human Genetics</orgName> <desc> <address> <addrLine>Roosevelt Drive - Headington, Oxford OX3 7BN</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington 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2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Lamb, Janine" sort="Lamb, Janine" uniqKey="Lamb J" first="Janine" last="Lamb">Janine Lamb</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128858" status="INCOMING"> <orgName>Wellcome Trust Centre for Human Genetics</orgName> <desc> <address> <addrLine>Roosevelt Drive - Headington, Oxford OX3 7BN</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>Royaume-Uni</country></affiliation></author><author><name sortKey="Sousa, Ines" sort="Sousa, Ines" uniqKey="Sousa I" first="Ines" last="Sousa">Ines Sousa</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128858" status="INCOMING"> <orgName>Wellcome Trust Centre for Human Genetics</orgName> <desc> <address> <addrLine>Roosevelt Drive - Headington, Oxford OX3 7BN</addrLine> <country key="GB"></country> </address> </desc> <listRelation> <relation active="#struct-302612" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-302612" type="direct"><org type="institution" xml:id="struct-302612" status="VALID"> <orgName>University of Oxford [Oxford]</orgName> <desc> <address> <addrLine>Wellington Square, Oxford OX1 2JD</addrLine> <country key="GB"></country> </address> <ref type="url">http://www.ox.ac.uk/</ref> </desc> 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Chicago</orgName></affiliation></author><author><name sortKey="Leventhal, Bennett" sort="Leventhal, Bennett" uniqKey="Leventhal B" first="Bennett" last="Leventhal">Bennett Leventhal</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-200668" status="INCOMING"> <orgName>Department of Child and Adolescent Psychiatry</orgName> <desc> <address> <addrLine>NYU Child Study Center - 70 Washington Square S, New York, NY 10012</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-300459" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300459" type="direct"><org type="institution" xml:id="struct-300459" status="VALID"> <orgName>New York University [New York]</orgName> <desc> <address> <addrLine>70 Washington Square South, New York, NY 10012</addrLine> <country key="US"></country> </address> <ref type="url">http://www.nyu.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Salt, Jeff" sort="Salt, Jeff" uniqKey="Salt J" first="Jeff" last="Salt">Jeff Salt</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128859" status="VALID"> <orgName>Department of Psychiatry [Pittsburgh]</orgName> <desc> <address> <addrLine>Thomas Detre Hall of the Western Psychiatric Institute and Clinic, University of Pittsburgh, 3811 O'Hara Street, Pittsburgh, PA 15213</addrLine> <country key="US"></country> </address> <ref type="url">http://www.wpic.pitt.edu/</ref> </desc> <listRelation> <relation active="#struct-309229" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-309229" type="direct"><org type="institution" xml:id="struct-309229" status="VALID"> <orgName>University of Pittsburgh School of Medicine [Pittsburgh]</orgName> <desc> <address> <addrLine>4200 Fifth AvenuePittsburgh, PA 15260</addrLine> <country key="US"></country> </address> <ref type="url">http://www.pitt.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Lord, Catherine" sort="Lord, Catherine" uniqKey="Lord C" first="Catherine" last="Lord">Catherine Lord</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128932" status="INCOMING"> <orgName>Autism and Communicative Disorders Centre</orgName> <desc> <address> <addrLine>Ann Arbor, Michigan</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-24332" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-24332" type="direct"><org type="institution" xml:id="struct-24332" status="VALID"> <orgName>University of Michigan [Ann Arbor]</orgName> <desc> <address> <addrLine>500 Church Street Ann Arbor, MI 48109-1090</addrLine> <country key="US"></country> </address> <ref type="url">http://www.umich.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Corsello, Christina" sort="Corsello, Christina" uniqKey="Corsello C" first="Christina" last="Corsello">Christina Corsello</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128932" status="INCOMING"> <orgName>Autism and Communicative Disorders Centre</orgName> <desc> <address> <addrLine>Ann Arbor, Michigan</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-24332" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-24332" type="direct"><org type="institution" xml:id="struct-24332" status="VALID"> <orgName>University of Michigan [Ann Arbor]</orgName> <desc> <address> <addrLine>500 Church Street Ann Arbor, MI 48109-1090</addrLine> <country key="US"></country> </address> <ref type="url">http://www.umich.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Hus, Vanessa" sort="Hus, Vanessa" uniqKey="Hus V" first="Vanessa" last="Hus">Vanessa Hus</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128932" status="INCOMING"> <orgName>Autism and Communicative Disorders Centre</orgName> <desc> <address> <addrLine>Ann Arbor, Michigan</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-24332" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-24332" type="direct"><org type="institution" xml:id="struct-24332" status="VALID"> <orgName>University of Michigan [Ann Arbor]</orgName> <desc> <address> <addrLine>500 Church Street Ann Arbor, MI 48109-1090</addrLine> <country key="US"></country> </address> <ref type="url">http://www.umich.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Weeks, Daniel" sort="Weeks, Daniel" uniqKey="Weeks D" first="Daniel" last="Weeks">Daniel Weeks</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-142567" status="INCOMING"> <orgName>Human Genetics Department</orgName> <desc> <address> <addrLine>4200 Fifth Ave, Pittsburgh, PA 15260</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-378064" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-378064" type="direct"><org type="institution" xml:id="struct-378064" status="INCOMING"> <orgName>University of Pittsburgh</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country><placeName><settlement type="city">Pittsburgh</settlement><region type="state">Pennsylvanie</region></placeName><orgName type="university">Université de Pittsburgh</orgName></affiliation></author><author><name sortKey="Volkmar, Fred" sort="Volkmar, Fred" uniqKey="Volkmar F" first="Fred" last="Volkmar">Fred Volkmar</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128985" status="INCOMING"> <orgName>Child Study Centre</orgName> <desc> <address> <addrLine>New Haven, Connecticut 0652</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-300737" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300737" type="direct"><org type="institution" xml:id="struct-300737" status="VALID"> <orgName>Yale School of Medicine</orgName> <desc> <address> <addrLine>333 Cedar Street New Haven CT 06510</addrLine> <country key="US"></country> </address> <ref type="url">http://medicine.yale.edu/</ref> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Tauber, Maite" sort="Tauber, Maite" uniqKey="Tauber M" first="Maïté" last="Tauber">Maïté Tauber</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-207731" status="INCOMING"> <orgName>Centre d'Endocrinologie, Maladies Osseuses, Génétique et Gynécologie Médicale</orgName> <desc> <address> <addrLine>330, avenue de Grande-Bretagne - TSA 70034 - 31059 Toulouse cedex 9</addrLine> <country key="FR"></country> </address> </desc> <listRelation> <relation active="#struct-300075" type="direct"></relation> <relation active="#struct-307239" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-300075" type="direct"><org type="institution" xml:id="struct-300075" status="VALID"> <orgName>CHU Toulouse [Toulouse]</orgName> <desc> <address> <addrLine>330 Avenue de Grande Bretagne, TSA 40031, 31059 Toulouse Cedex 09</addrLine> <country key="FR"></country> </address> </desc></org></tutelle><tutelle active="#struct-307239" type="direct"><org type="institution" xml:id="struct-307239" status="INCOMING"> <orgName>Hôpital des Enfants</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Fombonne, Eric" sort="Fombonne, Eric" uniqKey="Fombonne E" first="Eric" last="Fombonne">Eric Fombonne</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-129063" status="INCOMING"> <orgName>Department of Child Psychiatry</orgName> <desc> <address> <addrLine>2300 rue Tupper, Montreal, H3H 1P3</addrLine> <country key="CA"></country> </address> </desc> <listRelation> <relation active="#struct-134741" type="direct"></relation> <relation active="#struct-312535" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-134741" type="direct"><org type="institution" xml:id="struct-134741" status="VALID"> <orgName>McGill University</orgName> <desc> <address> <addrLine>845, rue Sherbrooke O. Montréal (Québec) Canada H3A 0G4</addrLine> <country key="CA"></country> </address> <ref type="url">http://www.mcgill.ca/</ref> </desc> </org></tutelle><tutelle active="#struct-312535" type="direct"><org type="institution" xml:id="struct-312535" status="INCOMING"> <orgName>Montreal Children's Hospital</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>Canada</country><placeName><settlement type="city">Montréal</settlement><region type="state">Québec</region></placeName><orgName type="university">Université McGill</orgName></affiliation></author><author><name sortKey="Shih, Andy" sort="Shih, Andy" uniqKey="Shih A" first="Andy" last="Shih">Andy Shih</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-128935" status="INCOMING"> <orgName>Scientific Affairs</orgName> <desc> <address> <addrLine>2 Park Avenue, 11th Floor, New York, NY 10016</addrLine> <country key="US"></country> </address> </desc> <listRelation> <relation active="#struct-331243" type="direct"></relation> </listRelation> <tutelles><tutelle active="#struct-331243" type="direct"><org type="institution" xml:id="struct-331243" status="INCOMING"> <orgName>Autism Speaks</orgName> <desc> <address> <country key="FR"></country> </address> </desc> </org></tutelle></tutelles></hal:affiliation><country>États-Unis</country></affiliation></author><author><name sortKey="Meyer, Kacie" sort="Meyer, Kacie" uniqKey="Meyer K" first="Kacie" last="Meyer">Kacie Meyer</name><affiliation wicri:level="1"><hal:affiliation type="institution" xml:id="struct-183914" status="VALID"> <orgName>University of Iowa [Iowa]</orgName> <desc> <address> <addrLine>Iowa City, IA 52242</addrLine> <country key="US"></country> </address> </desc> </hal:affiliation><country>États-Unis</country></affiliation></author></analytic><idno type="DOI">10.1038/ng1985</idno><series><title level="j">Nature Genetics</title><idno type="ISSN">1061-4036</idno><imprint><date type="datePub">2007-03</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Autism spectrum disorders (ASDs) are common, heritable neurodevelopmental conditions. The genetic architecture of ASDs is complex, requiring large samples to overcome heterogeneity. Here we broaden coverage and sample size relative to other studies of ASDs by using Affymetrix 10K SNP arrays and 1,181 [corrected] families with at least two affected individuals, performing the largest linkage scan to date while also analyzing copy number variation in these families. Linkage and copy number variation analyses implicate chromosome 11p12-p13 and neurexins, respectively, among other candidate loci. Neurexins team with previously implicated neuroligins for glutamatergic synaptogenesis, highlighting glutamate-related genes as promising candidates for contributing to ASDs.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Canada</li><li>France</li><li>Grèce</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Illinois</li><li>Iowa</li><li>Missouri (État)</li><li>Ontario</li><li>Pennsylvanie</li><li>Québec</li></region><settlement><li>Chicago</li><li>Iowa City</li><li>Montréal</li><li>Pittsburgh</li><li>Saint-Louis (Missouri)</li><li>Toronto</li></settlement><orgName><li>Université McGill</li><li>Université Washington de Saint-Louis</li><li>Université de Pittsburgh</li><li>Université de Toronto</li><li>Université de l'Illinois à Chicago</li><li>Université de l'Iowa</li></orgName></list><tree><country name="Canada"><noRegion><name sortKey="Szatmari, Peter" sort="Szatmari, Peter" uniqKey="Szatmari P" first="Peter" last="Szatmari">Peter Szatmari</name></noRegion><name sortKey="Brian, Jessica" sort="Brian, Jessica" uniqKey="Brian J" first="Jessica" last="Brian">Jessica Brian</name><name sortKey="Bryson, Susan" sort="Bryson, Susan" uniqKey="Bryson S" first="Susan" last="Bryson">Susan Bryson</name><name sortKey="Feuk, Lars" sort="Feuk, Lars" uniqKey="Feuk L" first="Lars" last="Feuk">Lars Feuk</name><name sortKey="Fombonne, Eric" sort="Fombonne, Eric" uniqKey="Fombonne E" first="Eric" last="Fombonne">Eric Fombonne</name><name sortKey="Liu, Xiao Qing" sort="Liu, Xiao Qing" uniqKey="Liu X" first="Xiao-Qing" last="Liu">Xiao-Qing Liu</name><name sortKey="Marshall, Christian" sort="Marshall, Christian" uniqKey="Marshall C" first="Christian" last="Marshall">Christian Marshall</name><name sortKey="Paterson, Andrew" sort="Paterson, Andrew" uniqKey="Paterson A" first="Andrew" last="Paterson">Andrew Paterson</name><name sortKey="Qian, Cheng" sort="Qian, Cheng" uniqKey="Qian C" first="Cheng" last="Qian">Cheng Qian</name><name sortKey="Roberts, Wendy" sort="Roberts, Wendy" uniqKey="Roberts W" first="Wendy" last="Roberts">Wendy Roberts</name><name sortKey="Scherer, Stephen" sort="Scherer, Stephen" uniqKey="Scherer S" first="Stephen" last="Scherer">Stephen Scherer</name><name sortKey="Senman, Lili" sort="Senman, Lili" uniqKey="Senman L" first="Lili" last="Senman">Lili Senman</name><name sortKey="Skaug, Jennifer" sort="Skaug, Jennifer" uniqKey="Skaug J" first="Jennifer" last="Skaug">Jennifer Skaug</name><name sortKey="Thompson, Ann" sort="Thompson, Ann" uniqKey="Thompson A" first="Ann" last="Thompson">Ann Thompson</name><name sortKey="Vincent, John" sort="Vincent, John" uniqKey="Vincent J" first="John" last="Vincent">John Vincent</name><name sortKey="Zwaigenbaum, Lonnie" sort="Zwaigenbaum, Lonnie" uniqKey="Zwaigenbaum L" first="Lonnie" last="Zwaigenbaum">Lonnie Zwaigenbaum</name></country><country name="États-Unis"><noRegion><name sortKey="Jones, Marshall" sort="Jones, 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uniqKey="Cook E" first="Edwin" last="Cook">Edwin Cook</name><name sortKey="Corsello, Christina" sort="Corsello, Christina" uniqKey="Corsello C" first="Christina" last="Corsello">Christina Corsello</name><name sortKey="Cuccaro, Michael" sort="Cuccaro, Michael" uniqKey="Cuccaro M" first="Michael" last="Cuccaro">Michael Cuccaro</name><name sortKey="Davis, Kenneth" sort="Davis, Kenneth" uniqKey="Davis K" first="Kenneth" last="Davis">Kenneth Davis</name><name sortKey="Dawson, Geraldine" sort="Dawson, Geraldine" uniqKey="Dawson G" first="Geraldine" last="Dawson">Geraldine Dawson</name><name sortKey="Devlin, Bernie" sort="Devlin, Bernie" uniqKey="Devlin B" first="Bernie" last="Devlin">Bernie Devlin</name><name sortKey="Estes, Annette" sort="Estes, Annette" uniqKey="Estes A" first="Annette" last="Estes">Annette Estes</name><name sortKey="Flodman, Pamela" sort="Flodman, Pamela" uniqKey="Flodman P" first="Pamela" last="Flodman">Pamela Flodman</name><name sortKey="Folstein, Susan" sort="Folstein, Susan" uniqKey="Folstein S" first="Susan" last="Folstein">Susan Folstein</name><name sortKey="Geschwind, Daniel" sort="Geschwind, Daniel" uniqKey="Geschwind D" first="Daniel" last="Geschwind">Daniel Geschwind</name><name sortKey="Gilbert, John" sort="Gilbert, John" uniqKey="Gilbert J" first="John" last="Gilbert">John Gilbert</name><name sortKey="Gilliam, Conrad" sort="Gilliam, Conrad" uniqKey="Gilliam C" first="Conrad" last="Gilliam">Conrad Gilliam</name><name sortKey="Goedken, Rhinda" sort="Goedken, Rhinda" uniqKey="Goedken R" first="Rhinda" last="Goedken">Rhinda Goedken</name><name sortKey="Guter, Stephen" sort="Guter, Stephen" uniqKey="Guter S" first="Stephen" last="Guter">Stephen Guter</name><name sortKey="Haines, Jonathan" sort="Haines, Jonathan" uniqKey="Haines J" first="Jonathan" last="Haines">Jonathan Haines</name><name sortKey="Hallmayer, Joachim" sort="Hallmayer, Joachim" uniqKey="Hallmayer J" first="Joachim" last="Hallmayer">Joachim Hallmayer</name><name sortKey="Herbert, Martha" sort="Herbert, Martha" uniqKey="Herbert M" first="Martha" last="Herbert">Martha Herbert</name><name sortKey="Hollander, Eric" sort="Hollander, Eric" uniqKey="Hollander E" first="Eric" last="Hollander">Eric Hollander</name><name sortKey="Hus, Vanessa" sort="Hus, Vanessa" uniqKey="Hus V" first="Vanessa" last="Hus">Vanessa Hus</name><name sortKey="Klei, Lambertus" sort="Klei, Lambertus" uniqKey="Klei L" first="Lambertus" last="Klei">Lambertus Klei</name><name sortKey="Korvatska, Elena" sort="Korvatska, Elena" uniqKey="Korvatska E" first="Elena" last="Korvatska">Elena Korvatska</name><name sortKey="Lajonchere, Clara" sort="Lajonchere, Clara" uniqKey="Lajonchere C" first="Clara" last="Lajonchere">Clara Lajonchere</name><name sortKey="Ledbetter, David" sort="Ledbetter, David" uniqKey="Ledbetter D" first="David" last="Ledbetter">David Ledbetter</name><name sortKey="Lese Martin, Christa" sort="Lese Martin, Christa" uniqKey="Lese Martin C" first="Christa" last="Lese-Martin">Christa Lese-Martin</name><name sortKey="Leventhal, Bennett" sort="Leventhal, Bennett" uniqKey="Leventhal B" first="Bennett" last="Leventhal">Bennett Leventhal</name><name sortKey="Lord, Catherine" sort="Lord, Catherine" uniqKey="Lord C" first="Catherine" last="Lord">Catherine Lord</name><name sortKey="Lotspeich, Linda" sort="Lotspeich, Linda" uniqKey="Lotspeich L" first="Linda" last="Lotspeich">Linda Lotspeich</name><name sortKey="Mangin, La Vonne" sort="Mangin, La Vonne" uniqKey="Mangin L" first="La Vonne" last="Mangin">La Vonne Mangin</name><name sortKey="Meyer, Kacie" sort="Meyer, Kacie" uniqKey="Meyer K" first="Kacie" last="Meyer">Kacie Meyer</name><name sortKey="Miller, Janet" sort="Miller, Janet" uniqKey="Miller J" first="Janet" last="Miller">Janet Miller</name><name sortKey="Minshew, Nancy" sort="Minshew, Nancy" uniqKey="Minshew N" first="Nancy" last="Minshew">Nancy Minshew</name><name sortKey="Munson, Jeff" sort="Munson, Jeff" uniqKey="Munson J" first="Jeff" last="Munson">Jeff Munson</name><name sortKey="Pericak Vance, Margaret" sort="Pericak Vance, Margaret" uniqKey="Pericak Vance M" first="Margaret" last="Pericak-Vance">Margaret Pericak-Vance</name><name sortKey="Piven, Joseph" sort="Piven, Joseph" uniqKey="Piven J" first="Joseph" last="Piven">Joseph Piven</name><name sortKey="Rodier, Patricia" sort="Rodier, Patricia" uniqKey="Rodier P" first="Patricia" last="Rodier">Patricia Rodier</name><name sortKey="Salt, Jeff" sort="Salt, Jeff" uniqKey="Salt J" first="Jeff" last="Salt">Jeff Salt</name><name sortKey="Samango Sprouse, Carol" sort="Samango Sprouse, Carol" uniqKey="Samango Sprouse C" first="Carol" last="Samango-Sprouse">Carol Samango-Sprouse</name><name sortKey="Schellenberg, Gerard" sort="Schellenberg, Gerard" uniqKey="Schellenberg G" first="Gerard" last="Schellenberg">Gerard Schellenberg</name><name sortKey="Segre, Alberto" sort="Segre, Alberto" uniqKey="Segre A" first="Alberto" last="Segre">Alberto Segre</name><name sortKey="Sheffield, Val" sort="Sheffield, Val" uniqKey="Sheffield V" first="Val" last="Sheffield">Val Sheffield</name><name sortKey="Shih, Andy" sort="Shih, Andy" uniqKey="Shih A" first="Andy" last="Shih">Andy Shih</name><name sortKey="Silverman, Jeremy" sort="Silverman, Jeremy" uniqKey="Silverman J" first="Jeremy" last="Silverman">Jeremy Silverman</name><name sortKey="Smith, Moyra" sort="Smith, Moyra" uniqKey="Smith M" first="Moyra" last="Smith">Moyra Smith</name><name sortKey="Spence, Anne" sort="Spence, Anne" uniqKey="Spence A" first="Anne" last="Spence">Anne Spence</name><name sortKey="Spence, Sarah" sort="Spence, Sarah" uniqKey="Spence S" first="Sarah" last="Spence">Sarah Spence</name><name sortKey="Stodgell, Chris" sort="Stodgell, Chris" uniqKey="Stodgell C" first="Chris" last="Stodgell">Chris Stodgell</name><name sortKey="Sutcliffe, James" sort="Sutcliffe, James" uniqKey="Sutcliffe J" first="James" last="Sutcliffe">James Sutcliffe</name><name sortKey="Tepper, Ping Guo" sort="Tepper, Ping Guo" uniqKey="Tepper P" first="Ping Guo" last="Tepper">Ping Guo Tepper</name><name sortKey="Vieland, Veronica" sort="Vieland, Veronica" uniqKey="Vieland V" first="Veronica" last="Vieland">Veronica Vieland</name><name sortKey="Volkmar, Fred" sort="Volkmar, Fred" uniqKey="Volkmar F" first="Fred" last="Volkmar">Fred Volkmar</name><name sortKey="Wassink, Thomas" sort="Wassink, Thomas" uniqKey="Wassink T" first="Thomas" last="Wassink">Thomas Wassink</name><name sortKey="Weeks, Daniel" sort="Weeks, Daniel" uniqKey="Weeks D" first="Daniel" last="Weeks">Daniel Weeks</name><name sortKey="Wijsman, Ellen" sort="Wijsman, Ellen" uniqKey="Wijsman E" first="Ellen" last="Wijsman">Ellen Wijsman</name><name sortKey="Wright, Harry" sort="Wright, Harry" uniqKey="Wright H" first="Harry" last="Wright">Harry Wright</name><name sortKey="Yu, Chang En" sort="Yu, Chang En" uniqKey="Yu C" first="Chang-En" last="Yu">Chang-En Yu</name></country><country name="France"><noRegion><name sortKey="Betancur, Catalina" sort="Betancur, Catalina" uniqKey="Betancur C" first="Catalina" last="Betancur">Catalina Betancur</name></noRegion><name sortKey="Bourgeron, Thomas" sort="Bourgeron, Thomas" uniqKey="Bourgeron T" first="Thomas" last="Bourgeron">Thomas Bourgeron</name><name sortKey="Leboyer, Marion" sort="Leboyer, Marion" uniqKey="Leboyer M" first="Marion" last="Leboyer">Marion Leboyer</name><name sortKey="Mantoulan, Carine" sort="Mantoulan, Carine" uniqKey="Mantoulan C" first="Carine" last="Mantoulan">Carine Mantoulan</name><name sortKey="Roge, Bernadette" sort="Roge, Bernadette" uniqKey="Roge B" first="Bernadette" last="Rogé">Bernadette Rogé</name><name sortKey="Tanzi, Rudolph" sort="Tanzi, Rudolph" uniqKey="Tanzi R" first="Rudolph" last="Tanzi">Rudolph Tanzi</name><name sortKey="Tauber, Maite" sort="Tauber, Maite" uniqKey="Tauber M" first="Maïté" last="Tauber">Maïté Tauber</name><name sortKey="Weisblatt, Emma" sort="Weisblatt, Emma" uniqKey="Weisblatt E" first="Emma" last="Weisblatt">Emma Weisblatt</name></country><country name="Suède"><noRegion><name sortKey="Gillberg, Christopher" sort="Gillberg, Christopher" uniqKey="Gillberg C" first="Christopher" last="Gillberg">Christopher Gillberg</name></noRegion></country><country name="Allemagne"><noRegion><name sortKey="Nelson, Stan" sort="Nelson, Stan" uniqKey="Nelson S" first="Stan" last="Nelson">Stan Nelson</name></noRegion><name sortKey="Bolte, Sven" sort="Bolte, Sven" uniqKey="Bolte S" first="Sven" last="Bölte">Sven Bölte</name><name sortKey="Feineis Matthews, Sabine" sort="Feineis Matthews, Sabine" uniqKey="Feineis Matthews S" first="Sabine" last="Feineis-Matthews">Sabine Feineis-Matthews</name><name sortKey="Felder, B Rbel" sort="Felder, B Rbel" uniqKey="Felder B" first="B Rbel" last="Felder">B Rbel Felder</name><name sortKey="Herbrecht, Evelyn" sort="Herbrecht, Evelyn" uniqKey="Herbrecht E" first="Evelyn" last="Herbrecht">Evelyn Herbrecht</name><name sortKey="Klauck, Sabine" sort="Klauck, Sabine" uniqKey="Klauck S" first="Sabine" last="Klauck">Sabine Klauck</name><name sortKey="Poustka, Annemarie" sort="Poustka, Annemarie" uniqKey="Poustka A" first="Annemarie" last="Poustka">Annemarie Poustka</name><name sortKey="Poustka, Fritz" sort="Poustka, Fritz" uniqKey="Poustka F" first="Fritz" last="Poustka">Fritz Poustka</name><name sortKey="Schmotzer, Gabi" sort="Schmotzer, Gabi" uniqKey="Schmotzer G" first="Gabi" last="Schmötzer">Gabi Schmötzer</name><name sortKey="Schuster, Claudia" sort="Schuster, Claudia" uniqKey="Schuster C" first="Claudia" last="Schuster">Claudia Schuster</name><name sortKey="State, Matthew" sort="State, Matthew" uniqKey="State M" first="Matthew" last="State">Matthew State</name></country><country name="Italie"><noRegion><name sortKey="Coon, Hilary" sort="Coon, Hilary" uniqKey="Coon H" first="Hilary" last="Coon">Hilary Coon</name></noRegion><name sortKey="Bacchelli, Elena" sort="Bacchelli, Elena" uniqKey="Bacchelli E" first="Elena" last="Bacchelli">Elena Bacchelli</name><name sortKey="Blasi, Francesca" sort="Blasi, Francesca" uniqKey="Blasi F" first="Francesca" last="Blasi">Francesca Blasi</name><name sortKey="Carone, Simona" sort="Carone, Simona" uniqKey="Carone S" first="Simona" last="Carone">Simona Carone</name><name sortKey="Maestrini, Elena" sort="Maestrini, Elena" uniqKey="Maestrini E" first="Elena" last="Maestrini">Elena Maestrini</name><name sortKey="Mcmahon, William" sort="Mcmahon, William" uniqKey="Mcmahon W" first="William" last="Mcmahon">William Mcmahon</name><name sortKey="Toma, Claudio" sort="Toma, Claudio" uniqKey="Toma C" first="Claudio" last="Toma">Claudio Toma</name></country><country name="Royaume-Uni"><noRegion><name sortKey="Wittemeyer, Kerstin" sort="Wittemeyer, Kerstin" uniqKey="Wittemeyer K" first="Kerstin" last="Wittemeyer">Kerstin Wittemeyer</name></noRegion><name sortKey="Aldred, Catherine" sort="Aldred, Catherine" uniqKey="Aldred C" first="Catherine" last="Aldred">Catherine Aldred</name><name sortKey="Bailey, Anthony" sort="Bailey, Anthony" uniqKey="Bailey A" first="Anthony" last="Bailey">Anthony Bailey</name><name sortKey="Baird, Gillian" sort="Baird, Gillian" uniqKey="Baird G" first="Gillian" last="Baird">Gillian Baird</name><name sortKey="Barnby, Gabrielle" sort="Barnby, Gabrielle" uniqKey="Barnby G" first="Gabrielle" last="Barnby">Gabrielle Barnby</name><name sortKey="Berney, Tom" sort="Berney, Tom" uniqKey="Berney T" first="Tom" last="Berney">Tom Berney</name><name sortKey="Bolton, Patrick" sort="Bolton, Patrick" uniqKey="Bolton P" first="Patrick" last="Bolton">Patrick Bolton</name><name sortKey="Francis, Kostas" sort="Francis, Kostas" uniqKey="Francis K" first="Kostas" last="Francis">Kostas Francis</name><name sortKey="Green, Jonathan" sort="Green, Jonathan" uniqKey="Green J" first="Jonathan" last="Green">Jonathan Green</name><name sortKey="Honeyman, Gemma" sort="Honeyman, Gemma" uniqKey="Honeyman G" first="Gemma" last="Honeyman">Gemma Honeyman</name><name sortKey="Hutchinson, Aislinn" sort="Hutchinson, Aislinn" uniqKey="Hutchinson A" first="Aislinn" last="Hutchinson">Aislinn Hutchinson</name><name sortKey="Kobayashi, Kazuhiro" sort="Kobayashi, Kazuhiro" uniqKey="Kobayashi K" first="Kazuhiro" last="Kobayashi">Kazuhiro Kobayashi</name><name sortKey="Lamb, Janine" sort="Lamb, Janine" uniqKey="Lamb J" first="Janine" last="Lamb">Janine Lamb</name><name sortKey="Le Couteur, Ann" sort="Le Couteur, Ann" uniqKey="Le Couteur A" first="Ann" last="Le Couteur">Ann Le Couteur</name><name sortKey="Mcconachie, Helen" sort="Mcconachie, Helen" uniqKey="Mcconachie H" first="Helen" last="Mcconachie">Helen Mcconachie</name><name sortKey="Monaco, Anthony" sort="Monaco, Anthony" uniqKey="Monaco A" first="Anthony" last="Monaco">Anthony Monaco</name><name sortKey="Parr, Jeremy" sort="Parr, Jeremy" uniqKey="Parr J" first="Jeremy" last="Parr">Jeremy Parr</name><name sortKey="Pickles, Andrew" sort="Pickles, Andrew" uniqKey="Pickles A" first="Andrew" last="Pickles">Andrew Pickles</name><name sortKey="Rutter, Michael" sort="Rutter, Michael" uniqKey="Rutter M" first="Michael" last="Rutter">Michael Rutter</name><name sortKey="Sousa, Ines" sort="Sousa, Ines" uniqKey="Sousa I" first="Ines" last="Sousa">Ines Sousa</name><name sortKey="Sykes, Nuala" sort="Sykes, Nuala" uniqKey="Sykes N" first="Nuala" last="Sykes">Nuala Sykes</name><name sortKey="Wallace, Simon" sort="Wallace, Simon" uniqKey="Wallace S" first="Simon" last="Wallace">Simon Wallace</name><name sortKey="Wilkinson, Julie Anne" sort="Wilkinson, Julie Anne" uniqKey="Wilkinson J" first="Julie-Anne" last="Wilkinson">Julie-Anne Wilkinson</name></country><country name="Grèce"><noRegion><name sortKey="Tsiantis, John" sort="Tsiantis, John" uniqKey="Tsiantis J" first="John" last="Tsiantis">John Tsiantis</name></noRegion><name sortKey="Papanikolaou, Katerina" sort="Papanikolaou, Katerina" uniqKey="Papanikolaou K" first="Katerina" last="Papanikolaou">Katerina Papanikolaou</name></country><country name="Pays-Bas"><noRegion><name sortKey="Van Engeland, Herman" sort="Van Engeland, Herman" uniqKey="Van Engeland H" first="Herman" last="Van Engeland">Herman Van Engeland</name></noRegion><name sortKey="De Jonge, Maretha" sort="De Jonge, Maretha" uniqKey="De Jonge M" first="Maretha" last="De Jonge">Maretha De Jonge</name><name sortKey="Hijmans, Channa" sort="Hijmans, Channa" uniqKey="Hijmans C" first="Channa" last="Hijmans">Channa Hijmans</name><name sortKey="Kemner, Chantal" sort="Kemner, Chantal" uniqKey="Kemner C" first="Chantal" last="Kemner">Chantal Kemner</name><name sortKey="Koop, Frederieke" sort="Koop, Frederieke" uniqKey="Koop F" first="Frederieke" last="Koop">Frederieke Koop</name><name sortKey="Langemeijer, Marjolein" sort="Langemeijer, Marjolein" uniqKey="Langemeijer M" first="Marjolein" last="Langemeijer">Marjolein Langemeijer</name><name sortKey="Staal, Wouter" sort="Staal, Wouter" uniqKey="Staal W" first="Wouter" last="Staal">Wouter Staal</name></country></tree></affiliations></record>Pour manipuler 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